Sound radix 32 lives 2.0 trial#

Main Outcomes and Measures The primary outcome was gender dysphoria, as measured by the Gender Preoccupation and Stability Questionnaire. This design ensured no individuals would be waiting longer than the time to standard care. Interventions Immediate initiation of testosterone commencement (intervention group) or no treatment (standard care waiting list of 3 months before commencement). Participants included transgender and gender-diverse adults aged 18 to 70 years seeking initiation of testosterone therapy.

Sound radix 32 lives 2.0 trial#

Objective To assess the effect of testosterone therapy compared with no treatment on gender dysphoria, depression, and suicidality in transgender and gender-diverse adults seeking masculinization.ĭesign, Setting, and Participants A 3-month open-label randomized clinical trial was conducted at endocrinology outpatient clinics and primary care clinics specializing in transgender and gender-diverse health in Melbourne, Australia, from November 1, 2021, to July 22, 2022. Observational studies have reported associations between commencement of gender-affirming hormone therapy and improvements in gender dysphoria and depression, but there is a lack of data from randomized clinical trials. Importance Testosterone treatment is a necessary component of care for some transgender and gender-diverse individuals. Shared Decision Making and Communication.

Scientific Discovery and the Future of Medicine.Health Care Economics, Insurance, Payment.

Clinical Implications of Basic Neuroscience.Challenges in Clinical Electrocardiography.